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Contextually, the concentration of dopamine grows in the reward areas of the brain, evoking the so-called stereotypical exhilaration and relaxation effects. As a consequence, this dopamine flood in the reward pathway is distinctively associated with the addiction to the drug (Comer and Cahill, 2019)

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Data were stored and exported to Matlab for further analysis, which was performed by thresholding the curves using an empirically derived threshold, to detect the mEPSCs