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It also plays a role in energy homeostasis and cellular metabolism

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This marker is more accurate in assessing the biologically active fraction of vitamin B 12 in circulation than serum B 12 itself, and its level correlates well with the concentration of vitamin B 12 in erythrocytes (Valente et al., 2011)

Healthy donor samples were collected under the SingHealth Centralised Institutional Review Board (CIRB Ref: 2017/2806) and HSA Residual Blood Samples for Research project titled Blood biomarkers of immune-related diseases (Ref: #201306-05)