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Description

B12 plays a crucial role in energy metabolism, red blood cell formation, and neurological function, contributing to a quick energy boost and overall vitality

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It explores NOs influence on critical signaling pathways (Wnt/-catenin, PI3K/AKT/mTOR, and NF-B), immune modulation through pro-tumorigenic immune cell polarization, and metabolic reprogramming to sustain tumor growth and therapy resistance

Each case of B12 deficiency may have a different combination of symptoms, probably depending on the persons folate levels (Sobczyska-Malefora et al., 2021)

Organoids were harvested at day 7 (Matrigel) or day 4 (collagen), with both conditions collected at passage 2, each representing comparable growth stages for scRNA-seq analysis