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SKU: 70965056244
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Description

The resulting inflammatory environment contributes to synaptic loss and cognitive decline

Cyanocobalamin is the most widely available synthetic form, is shelf-stable, and is FDA-approved for treating B12 deficiency

2 Dilute the resultant culture into 7H9 media containing 0.2% succinate and kanamycin at an OD 600 of 0.02, and incubate with shaking at 37 C to an OD 600 of 0.40.5 (~15 hr)

Importantly, as the chief brain source of APOE, astrocytes, especially those expressing the APOE4 allele, promote A aggregation, tau pathologies, BBB breakdown, and cerebrovascular dysfunctions (Wang M