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The results have been consistently promising across multiple tissue types and organ systems, though large-scale human clinical trials remain limited

Post-Exertional Malaise (PEM): While not a cure for PEM, improving mitochondrial efficiency and reducing systemic oxidative stress can help raise a patient's energy envelope, making them slightly more resilient to the metabolic fallout of physical or cognitive exertion

Adults over 50 are at a higher risk for a B12 deficiency

Additionally, controlling hunger and increasing energy can positively affect mental well-being, contributing to a holistic approach to health