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Oligodendrocyte dysfunction in amyotrophic lateral sclerosis: mechanisms and therapeutic perspectives

Whether you're training for a race, recovering from an intense workout, or just getting back into a fitness routine, physical activity takes a toll on the body

Among CagriSema-treated participants, 73.5% achieved HbA1c of 6.5% or below compared to 15.9% with placebo, demonstrating remarkable dual efficacy for both weight and glycemic endpoints

These results demonstrate that metformin suppresses TXNIP expression through mitochondrial complex 1 inhibition, leading to the upregulation of GLUT1 expression and membrane localization in the ileum and colon, where it contributes to the glucotonic effect