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13% of the participants treated with the combined compound ended up discontinuing the trial, while 10% of the participants treated with semaglutide discontinued, however, none of the participants treated with cagrilintide discontinued their treatment plan indicating that cagrilintide was the most well tolerated by the study participants [2]

Type 2 Diabetes Focus Tirzepatide Tirzepatide has 5 SURPASS T2D trials, FDA approval for diabetes (Mounjaro), and demonstrated superiority over semaglutide in SURPASS-2