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If irritation continues beyond two hours, consult a doctor

While preclinical data suggest that prodromal-stage modulation of the NTF-mitochondria axis may reduce neuronal loss, translating this finding to humans requires reliable biomarkers (e.g., cerebrospinal fluid -synuclein oligomers, mitochondrial DNA mutation burden) and imaging tools (e.g., dopamine transporter PET) for precise disease staging

Residual physical problems As is the case for psychiatric problems, there are a number of physical problems that either appear after drug use is over, or that begin during the period of drug use but persist long afterwards