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Despite appearing less harmful, the high nicotine levels signal caution due to the potential for similar dependence as with traditional smoking

236 Grumet cites the Colonial Records of Pennsylvania, 8: 416)) By the end of the eighteenth century, the Munsee who had previously migrated to the upper Susquehanna region were living in Seneca communities

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Moreover, the urine levels of metabolites of acrylonitrile, acrolein, propylene oxide, acrylamide and crotonaldehyde, all of which are detrimental for human health, were significantly higher in e-cigarette -only users than in non-smoker controls, reaching up to twice the registered values of those from non-smoker subjects (Table 1) [9]