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Ferroptosis of retinal cells, such as RPE, photoreceptor, and RGC, has been reported to be involved in the progression of age-related/inherited macular degeneration, blue light-induced retinal degeneration, glaucoma, DR, and retinal damage caused by retinal ischemia-reperfusion (I/R) (Figure 1

also found the knockdown of STING down-regulated expression of ISG15 and ROS-related genes, including HECT domain and RCC1-Like Domain-Containing Protein 5 (HERC5), kruppel-like factor 4 (KLF4), and dual oxidase 2 (DUOX2) (7376)