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Exosomes from high glucose-treated macrophages activate glomerular mesangial cells via TGF-1/Smad3 pathway in vivo and in vitro

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Transplantation of faecal microorganisms (FMT) from healthy mice into male mice placed on a high-fat diet (HFD) can restore bacterial diversity, improves metabolism associated with poor dietary patterns and reduces hippocampal astrocyte hyperplasia, supporting the role of ecological dysregulation in mediating obesity-induced cognitive impairment (60)