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Loss of TMEM106B ameliorates lysosomal and frontotemporal Dementia-Related phenotypes in Progranulin-Deficient mice

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Positive findings were also obtained in the heart of Wistar albino rats exposed at 75 and 150 mg/kg bw per day by oral gavage for 4 weeks (Al-Eisa et al., 2018) and in the liver of rats exposed at 75 and 150 mg/kg bw per day by oral gavage for 30 days (Hamza et al., 2019)