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These chronic attributes are generally associated with selective degeneration of dopaminergic neurons, corollary de-pigmentation of substantia nigra pars compacta (SNpc) and concomitant accumulation of -synuclein in insoluble inclusions called Lewy bodies 2,3

USA 111 , 1421714222 (2014)

The procedure to locate the voxel for the IFC was: (a) center the voxel at the first axial slice above the ventricles at the height of one third of the sagittal midline and at the width center of the left hemisphere, (b) from the sagittal view locate the center length of the voxel parallel to the inferior frontal sulcus and locate the length over the inferior frontal junction, and (c) from the coronal view, locate the top of the voxel parallel to the cortical surface

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