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The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS

Dr Krista LaBruzzo, an addiction medicine specialist, adds: "This combination of natural water loss and alcohol's dehydrating effects can lead to hangovers, headaches and even confusion." [1] When combined with slower metabolism and reduced liver efficiency, this lower water retention makes hangovers after 40 even more intense