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Some of these factors were discussed more generally, in the February 2016 proposed rule, with respect to our consideration of options for further developing our reopening policy (see, for example, 81 FR 5854 and 5855)

(2) Revisions In the CY 2025 PFS proposed rule (89 FR 61911), we explained that it is important to establish a policy that would allow CMS to proactively make similar adjustments for future calendar years, should new SAHS billing activity be identified

For a broader overview of peptide handling best practices, see our guides on How to Store Research Peptides and What Are Research Peptides