glutathione micromolar measurement Frontiers Glutathione Biochemistry | Glutathione Synthesis

When the effects of antineoplastic drugs are considered, it was demonstrated that the treatment with doxorubicin (DOX), an anticancer drug belonging to the anthracycline class, lowered GSH levels in cancer cells, and that exogenous GSH could increase cytosolic GSH levels, thus highly reducing collateral effects of DOX, such as cardiotoxicity and hepatotoxicity

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EMBO J 30:20442056 Mari M, Morales A, Colell A, Garcia-Ruiz C, Kaplowitz N, Fernandez-Checa JC (2013) Mitochondrial glutathione: features, regulation and role in disease

40 The drug quickly caught the attention of criminal elements and smugglers who recognized that its rewarding properties surpassed those of morphine, the then-dominant abused drug