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Mutagenics, genotoxins, and cytotoxins have all been implicated in the development of cancers

The study also found that constipation levels peaked at about two weeks

The most widely publicized study into the safety of e-cigarettes was done when researchers analyzed two leading brands and concluded the devices did contain trace elements of hazardous compounds, including a chemical which is the main ingredient found in antifreeze

A long-term exposure study of IQOS (12 weeks) reported 20 times less toxicity on human bronchial epithelial cells regarding oxidative stress, DNA damage, and epithelial-to-mesenchymal transition (a marker of carcinogenesis) 61