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Abbreviations Used AMPSO 3-[(1,1-dimethyl-2-hydroxyethyl)amino]-2-hydroxypropanesulfonic acid Cdc M-phase inducer phosphatase 2 cDsbD C-terminal domain of DsbD CoA coenzyme A CoAS-SCoA coenzyme A dimer CoAS-SG gultathionylated CoA COX Cytochrome oxidase CySH Cys thiol CySSG Cys-GSH mixed disulfide CySOH Cys sulfenic acid CySO 2 H sulfinic acid Cys p peroxidative Cys of peroxiredoxins CyS-S(=O)Cy thiosulfinate ester DsbA-D the disulfide bond protein family A-D DTPA diethylenetriamine pentaacetic acid DTT dithiothreitol ER endoplasmic reticulum Ero1 ER oxidoreductin Erv1 essential for respiration and vegetative growth sulfhydryl oxidase FAD flavin adenine dinucleotide FOX Fe 2+ /xylenol orange assay GAPDH glyceraldehyde 3-phosphate dehydrogenase GOR glutathione oxido-reductase Gpx or Orp1 glutathione peroxidases Grx glutaredoxin GrxS-SG glutathionylated Grx GSH reduced glutathione GSSG oxidized glutathione HRP horseradish peroxidase Hot13 Zn binding protein HOX hypohalous acids HSA human serum albumin I27S 24 -S 55 I27 domain of human cardiac titin IMS mitochondrial inter membrane space iP phosphate buffer nDsbD N-terminal domain of DsbD OxyR the Escherichia coli transcription factor PDI protein disulfide isomerase Prx peroxiredoxins PTP protein tyrosine phosphatase QSOX quiescin-sulfhydryl oxidase RSOO thiyl peroxyl radical Srx sulfiredoxin Trx thioredoxin Tsa yeast peroxiredoxin TrxR thioredoxin reductase Yap1 Yes-associated protein 1 Acknowledgments The financial support of FP7-PEOPLE-2010-RG (Marie Curie International Reintegration Grant

PMID: 18815398

Part of that might actually be by increasing the amount of intracellular serotonin, both by increasing the synthesis of serotonin and also by increasing the transport of serotonin

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