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However, further research studies reported that glutathione supplements taken for this purpose lead to problems that may include allergic reactions with itchy and irritated skin, fatigue, and erythema-producing redness spots on the skin

Notably, NO is a signaling molecule produced by nitric oxide synthases (NOS), including endothelial (eNOS), neuronal (nNOS), and inducible (iNOS) nitric oxide synthases 76,77,78,79,80,81,82,83,84,85,86,87,88,89,90,91

Gene-editing therapies aim to correct the genetic defects or pathological processes underlying PD at their source, with the goal of directly intervening in the disease's genetic or molecular etiology, protecting neurons, and halting or delaying disease progression [214]

*Correspondence: Qiang Zeng, [email protected] ORCID: Qiang Zeng, orcid.org/0009-0003-5586-3321 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers