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Another particularity is that, while the myelin sheath itself is the main oligodendroglial feature, these cells are also known to guarantee axonal enlargement and stability during post-natal development through the release of neurotrophic factors ( The characteristics of CNS myelin may also be attributed to their molecular composition, as can be seen in Figure 1

developed a novel hypoxia-activated combination nanomedicine that targets hypoxic tumors through hypoxia-sensitive block copolymers and photothermal/photodynamic therapy (PTT/PDT), efficiently delivering drugs and achieving synergistic anticancer effects of chemotherapy and PDT/PTT, completely eliminating advanced breast cancer, including hypoxic and metastatic tumors, stimulating a systemic antitumor immune response, and significantly improving survival rates, showing important clinical application potential [500]

70(3c):1139-51

Becker K, Savvides SN, Keese M