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Subsequently, structural analysis showed that the 4Fe4S domain forms a channel with an arch domain, that can accommodate single-stranded DNA (ssDNA) (Fan et al., 2008

In the following sections of the manuscript, we emphasize the role of immunologic disturbances associated with G6PD deficiency, such as neutrophil dysfunction, impaired inflammasome activation, and disruption in the NF-B signaling pathway, which may contribute to increased ROS production, viral replication, and contagiousness in SARS-CoV-2 infection

The protein sequences used and their respective identities with homologs are presented in the Supplementary Table S2