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Kwong, M., Y.W

Nat Rev Immunol

3.5 Regulatory mechanisms of ferroptosis in IBD Indeed, the molecular mechanisms of ferroptosis are diverse, and several transcription factors (e.g., TP53, NFE2L2/NRF2, ATF3, ATF4, YAPTAZTFAP2CSPHIFAEPAS/HIFA BACH TFEBJUNHIC1, and HNF4A) play multiple roles through transcription-dependent or transcription-independent mechanisms play multiple roles in shaping ferroptosis susceptibility (28)

Ustekinumab versus adalimumab for induction and maintenance therapy in biologic-naive patients with moderately to severely active Crohns disease: a multicentre, randomised, double-blind, parallel-group, phase 3b trial