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Study results have suggested that wild-type (WT) BAP1 significantly decreased H2Aub occupancy on the promoter and gene body of xCT, but the C91A mutant did not exert this effect (71)

One anomaly from previous measurements was the high intracellular steady-state oxidation of roGFP2 for fusion contructs with ScGrx7, in particular, when a WP-motif or a loop from class II glutaredoxins was introduced

Reza iAR, Ranjan M, DHaese PF, Haut MW, Carpenter J, Najib U, Mehta RI, Chazen JL, Zibly Z, Yates JR, Hodde SL, Kaplitt M

Future research should focus on combination strategies that target multiple redox-regulating pathways simultaneously