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Anything not natural is immediately out

Carcinogenic Chemicals in Tobacco Smoke Tobacco smoke constitutes more than 4,000 compounds, of which over 70 with carcinogenic activities, such as polycyclic aromatic hydrocarbons (PAHs), nitrosamines, aromatic amines, and others ( N -dimethylnitrosamine (DMN, also known as N -nitrosodimethylamine), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), and N -nitrosonornicotine (NNN) ( N -nitrosamines and tobacco-specific nitrosamines (TSNAs) can attack DNA at the O6-position of guanine forming DNA adducts O6-methylguanine and O(6)-[4-oxo-4-(3-pyridyl) butyl]guanine (O6pobG)

In-depth interviews allow more detailed probing than is typically possible in a focus group and we used this opportunity to undertake a careful exploration of participants perceptions and rationalisations

Todays authorization represents the first product to successfully demonstrate the potential for these types of tobacco products to help reduce nicotine dependence among addicted smokers