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What if a single peptide could rebuild the structural communication networks inside your brain not just boost neurotransmitters temporarily, but physically generate new synaptic connections

Lentiviral particles for transduction were generated by cotransfection of lentiCRISPRv2 plasmids with second-generation lentiviral packaging plasmids (pMD2.g and psPAX2) or pMCB320 plasmids with third-generation lentiviral packaging plasmids (pMDLg/pRRE, pRSV-Rev and pMD2.G) into HEK293T cells using TransIT-LT1 transfection reagent (Mirus) according to the manufacturers instructions

The panel highlighted two FDA approved drugs, as well as a promising combination therapy in development

Glutamate is the most important transmitter for normal brain function, but excessive glutamate may cause toxic damage to the brain