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In the same study, aspartame at concentrations of up to 2000 g/mL did not induce sister-chromatid exchange (SCE) at 24 or 48 hours

Concentration (start) Volume (start) = Concentration (final) Volume (final) In Vivo : Select the appropriate dissolution method based on your experimental animal and administration route

Biological half-life Biological half-life ( elimination half-life , pharmacological half-life ) is the time taken for the concentration of a biological substance, such as a medication, to decrease from its maximum initial concentration (C max ) to the half of C max in the blood plasma