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doi:10.1073/pnas.81.11.3337

TNF- and IL-6: the link between immune and bone system

Among all OPTN mutations, E50K is the one most clearly shown to cause glaucoma

It is important to note that the common factors which relate to all these metabolic pathologies are cytokines and oxidative stress, which have been elucidated to have a raised impact that could explain these different pathologies, being all of them interconnected