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The classifier's performance was evaluated using a three-fold cross-validation approach

Preclinical evaluations encompass assessments of physicochemical parameters, stability, immunogenicity, and toxicity in both in vitro and in vivo contexts

revealed that butyrate directly binds to the TLR5 receptor on CD8+ T cells ( The findings of this research illustrate that Roseburia intestinalis protects against the development of CRC by generating butyrate, which subsequently boosts the efficacy of anti-PD-1 immunotherapy

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