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However, the mechanisms by which microneedling works (growth factor release, stem cell activation, enhanced drug delivery) are not gender-specific

Research on pancreatic cancer has revealed that the anticancer effects of oxymatrine may be attributed to the regulation of the Bcl-2 and inhibitors of apoptosis (IAP) families, the release of mitochondrial cytochrome c, and the activation of caspase-3 [229]

These characteristics position CSCs as significant factors in tumor recurrence and unfavorable clinical results, emphasizing their role as targets for therapy