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To analyze the daily exposure to metals, the levels found by Williams et al (reported for 10 puffs) were multiplied by 120, while those in the Goniewicz study (reported for 150 puffs) were multiplied by 8, after subtracting the reported environmental levels

Most adult smokers, about 80 percent, began taking a puff before the age of 18, says the Centers for Disease Control and Prevention

In the oral mucosa, where the ageing epithelial cells move faster to the surface compared to skin, a similar defence-mechanism seems to be present, cleaning the mucosa from different toxic chemicals penetrating the epithelium