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[7] Early detection and treatment prevent irreversible complications

So if you want to say like Well, how do you treat it? I think thats the thing is take a step back

Write the reconstitution date on the vial and discard any unused medication after 28 days have passed

Note on the tolerance/diminishing-effect claim: the widely repeated effect fades after 4 to 6 weeks figure appears as repeated online claims, not in any primary study I could locate