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A large amounts of studies found the role of oxidative stress in the pathogenesis of depression [46]

Barreto, Pontifical Xavierian University, Colombia

A phase 2 study (NCT01077921) showed decrease in adhesion molecules such as E-selectin and P-selectin but results were not statistically significant and no clinical endpoints were discussed ( Due to their P-selectin mediated adhesion inhibition properties, heparinoids have been additionally investigated with interesting results