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Description

Combinatorial targeting of glutamine metabolism and lysosomal-based lipid metabolism effectively suppresses glioblastoma

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Glucose tolerance, compound tolerance and insulin tolerance tests Mice were fasted for 5 h before being challenged with an intraperitoneal injection of 1.75 g kg 1 of glucose dissolved in isotonic saline

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variable bioavailability and formulation differences can blunt expected antioxidant effects in vivo -Lipoic acid (ALA) shows rapid absorption but short half-life and 2040% oral bioavailability, with marked inter-formulation variability

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