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If you develop severe allergic reactions such as difficulty breathing, facial swelling, or widespread rash after a B12 injection, call 999 or go to A&E immediately, as these may indicate anaphylaxis, though this is extremely rare

Injections should be administered following clinical assessment, and long-term or repeated use should be medically guided

In a 2020 study, researchers found a close link between Vitamin B12 deficiency and cognitive impairment showing that replacement therapy could be a strong option for improving patient cognitive outcomes

I almost always use a blunt cannula (at least a 25 gauge thickness) to do this treatment and I dont use extra thin cannulas (27 gauge or thinner) which can bend and can still be sharp at the tip (even though they are still called blunt)