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Recently, increasing studies have demonstrated the effect of IKK in the obesity-mediated inflammation [100]

In the first few paragraphs well address immediate reactions, less common systemic responses and what long-term use might mean

In this last case, transmethylation capacity is limited because the tissue distribution of the enzyme is restricted to specific organs (Delgado-Reyes et al., 2001)

This sensor configuration is also suitable for various similar applications, including droplet counting, light intensity, and size-based matter/structure sorting, and speed measurement as they traverse the sensor apertures