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Tissue-derived extracellular vesicles in cancers and non-cancer diseases: present and future

Despite the fact that conventional medical dogma holds tightly to the notion that primary Parkinson's disease truly lacks an identifiable cause (other than genetics in familial Parkinson's disease), metabolic phenomena, such as oxidative stress, mitochondrial fatigue, and other age-related abnormalities are linked with the death of dopamine-producing neurons

Because the list of potential differentialsincluding renal carcinoma, cholangiocarcinoma, mesenteric carcinoma, and ovarian carcinomawas broad, it was important to choose a chemotherapeutic protocol with activity across multiple carcinoma types, consistent with CUP treatment principles

Smith GD, Ebrahim S (2004) Mendelian randomization: prospects, potentials, and limitations