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However, synovial fluid loses much of its thickness and viscosity during osteoarthritis, causing increased pain and discomfort with joint movement while also allowing inflammatory cells released during osteoarthritis to contact sensory nerves in your joint

Minor injection site pain within 18 hours but then arm started to pull up at elbow and sharp nerve pain in wrist began on extension of arm

While advancements have been made in understanding the pathological mechanisms through research on animal models and clinical trials, there are still limitations to be addressed

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