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Neurobiol Dis 44(1):142151 Liu SX, Zhang Y, Wang YF et al (2012) Upregulation of heme oxygenase-1 expression by hydroxysafflor yellow A conferring protection from anoxia/reoxygenation-induced apoptosis in H9c2 cardiomyocytes

Breathing issues: In rare cases, one may experience difficulty in breathing due to glutathione

Then, 6-phosphogluconate dehydrogenase (PGD) that often functions as a homodimer catalyzes the oxidative decarboxylation of 6-phosphogluconate (6-PG) to synthesize ribulose-5-phosphate (Ru5P) and a second NADPH in the third reaction

Advani SM, Shi Q, Overman MJ, Loree JM, Lam M, Morris V, Shureiqi I, Kee B, Dasari A, Vilar E, Sarshekeh AM, Lin HK, Manuel S, Hamilton S, Raghav K, Maru D, Kopetz S , Wang XS