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Disclosure of interest: Gabriele Prandin: nothing to disclose

"Yes, you will go brown, because you will tan and the reason you will tan is because the drug itself enables the body to develop melanin

Conversely, guiding immune cells toward an anti-inflammatory phenotype, such as M2-skewed macrophages, can enhance lipid clearance and reduce iron overload in OA joints, potentially lowering ferroptosis incidence (109) ( Figure 2 )