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The authors thank for providing elements to make figures

It can be seen from the results that antioxidants can reduce blood glucose and improve proteinuria, which provides a good direction and idea for the clinical treatment of DKD and lays a good foundation for further clinical trials and more basic studies

Semaglutide, a modified GLP-1 (glucagon-like peptide-1) analog with extended half-life, provides complementary mechanisms including glucose-dependent insulin secretion, appetite regulation through hypothalamic pathways, and additional gastric emptying modulation

Regulation of c-MET signaling is also accomplished via its binding to various protein tyrosine phosphatases (PTPs), including the receptor-type PTPs density enhanced phosphatase 1 (dEP1) (or PTPrI) and leukocyte common antigen-related molecule (LAR) (or PTPrF) [Machide et al