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For example: Chemical mix changes: If the filter removes some strong-smelling compounds, the smoke may seem less intense

The Cochrane Review on NRT found that combination therapy pairing NRT (patches, gum, or lozenges) with a behavioral replacement increases quit rates by 15-25% compared to NRT alone

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Both showed a potential benefit for smoking cessation and high levels of continued e-cigarette use at the end of the intervention, but presented no long-term safety data, which aligns with the findings of our analysis.104 , 105 The patient engagement activities undertaken for this guideline to assess patient preferences included 19 individuals in phase 1 and 8 in phase 2, and were limited in terms of diversity, so may not be generalizable to the broader population