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Therefore, they are only used for laboratory and research purposes

[DOI] [PMC free article] [PubMed] [Google Scholar] Love C

Epidemiological, clinical and experimental studies show a link between elevated UA levels (or hyperuricemia) and increased risk for CVD, including arterial hypertension, CAD, atrial fibrillation (AF) and congestive heart failure (HF)

106,107 Aiming to evaluate the effect of lowering-Cu therapy in treating AD, several Cu chelators have been developed and tested in mouse models of AD, showing promising beneficial effects such as antioxidant properties, reduced A aggregation, and amelioration of neurological symptoms