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control+kyn, transfected with GPx2 empty lentivirus for 48 h, followed by treatment with 150 M kyn for 24 h

When we examined the metabolites individually, malate, fumarate, -hydroxyisovalerate, pyruvate and lactate were significantly elevated in pre-diagnostic glioblastoma patients (Supplementary Table S1), which they also were when all glioma pre-diagnostic cases were analyzed together (Fig

Although ADH5 is ubiquitously expressed in various animal and human tissues, expression levels of ADH5 may be widely variable between organs and cell types

3-bromopyruvate ameliorate autoimmune arthritis by modulating Th17/Treg cell differentiation and suppressing dendritic cell activation