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Abstract Based on the concept of the tripartite synapse, we have reviewed the role of glucose-derived compounds in glycolytic pathways in astroglial cells

Disclosures: Taranika Sarkar Das: Nothing to Disclose, Jahnavi Udaikumar: Nothing to Disclose, Kimberly Ho: Nothing to Disclose, Carolyn Wilson: Nothing to Disclose, Inna De Leon: Nothing to Disclose, Kripali Gautam: Nothing to Disclose, Xucong Meng: Nothing to Disclose, Jennifer Stromberg: Nothing to Disclose, Raiya Sarwar: Nothing to Disclose, Saikiran Kilaru: Nothing to Disclose, Bilal Hameed: Gilead: Grant/Research Support, Intercept: Grant/Research Support, Pliant: Grant/Research Support, Novo Nordisk: Grant/Research Support, Madrigal: Grant/Research Support, Salix: Grant/Research Support, Mallinckrodt: Advisor, Pleiogenix: Advisor, CLDF: Advisor, Gilead: Consultant, Pioneering Medicine VII Inc: Consultant, Surrozen: Consultant, Pleiogenix: Stock privately held company, Scholars In Medicine: Speaking and Teaching, Aasma Shaukat: Nothing to Disclose 947 PSYCHOLOGICAL BURDENS, SYSTEM DISTRUST, AND FINANCIAL CONSTRAINTS AMONG THE BARRIERS FACING MARGINALIZED GROUPS REFERRED FOR LIVER TRANSPLANTATION FOR HEPATOCELLULAR CARCINOMA: A QUALITATIVE STUDY Lauren Nephew 1 Courtney Moore 2 Nicole Garcia 1 Lisa Parks 2 Allison McKay 2 Alexandra Strauss 3 Sarah Wiehe 2 John Holden 1 Monica Kasting 4 Katie Ross-Driscoll 1 Marwan Ghabril 1 Eric Orman 1 Archita Desai 1 Naga Chalasani 5 Susan Rawl 1 , 1 Indiana University, 2 Indiana University Clinical and Translational Science Institute, 3 Johns Hopkins University, 4 Purdue University, 5 Indiana University Medical Center Background: Black patients and those experiencing adverse social determinants of health (SDOH) face significant disparities in accessing curative therapies for hepatocellular carcinoma (HCC), impacting their survival

the therapy cycle can be repeated according to the judgment of the skilled clinician