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It is responsible for transporting Cu + from the cytoplasm to the intermembrane space of mitochondria to the synthesis of cytochrome c oxidase 1 (SCO1) and cytochrome c oxidase (CCO), thus maintaining the normal function of enzymes in the respiratory chain (19)

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114,115,116,117 FOXC1 activates the PI3K/AKT signaling pathway, leading to the phosphorylation and activation of several downstream proteins, such as NF-B and GSK3-

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