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Given their role in mediating migration and invasiveness, resistance to irradiation and maintenance of the glioma SC pool, both HGF/c-MET and TGF- signaling pathways have been considered as potential therapeutic targets

On paper, CagriSema produced a marginally higher percentage in slightly less time

However, unlike the hits obtained from the P3 1 21 XChem screen, the hits from the P4 1 2 1 2 XChem screen spanned a larger surface area of the TIN2 TBM binding site (Fig