glutathione reductase enzyme inhibitor human Role of glutathione reductase (GR)

GSH From Antioxidant to Post-Translational Modifier (PMC, 2016) S-Glutathionylation as a Major Redox Signalling Mechanism A review published in PMC, authored by a leading researcher in the field, documented GSHs evolution in the scientific literature from a simple antioxidant to a key post-translational modifier through S-glutathionylation the reversible formation of mixed disulfides between GSH and protein cysteine residues

Additionally, the small GTPase Rab10 is critical for sorting internalized TrkB into signaling endosomes for retrograde transport, a process essential for propagating neurotrophic signals from synapses to the cell body

Neutrophil extracellular traps (NETs) - formation and implications

Nicklin, P