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doi: 10.1007/s12015-024-10701-x 58 SasakiTKurokoMSekineSMatsuiSKikuchiOSusantiVYet al

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Oral treatment with CuII(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis

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By leveraging SFNs ability to induce oxidative stress and deplete thiol levels in parasites, this approach can enhance the efficacy of artemisinin and potentially restore its effectiveness against resistant strains

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