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Such systems biology perspectives not only drive fundamental understanding of comorbidity mechanisms but also provide a theoretical foundation for developing next-generation trans-organ therapeutic strategies targeting systemic immunometabolic homeostasis

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However, bioinformatic analysis revealed that many prokaryotic species that encode GSH-dependent proteins lack the gene for this enzyme

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Considering that multiple stress-response cis -acting elements were predicted in the promoters of GhGPX genes (Table 2), we used qRT-PCR to investigate the expression profiles of GhGPXs when the plants were under high-temperature, high-salinity, osmotic and heavy-metal stress

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