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Hemoglobin that has little oxygen bound to it loses much of its brightness, so that blood returning to the heart is more burgundy (bluish red) in color.Considering that cellular respiration continuously produces carbon dioxide, the partial pressure of carbon dioxide is lower in the blood than it is in the tissue, causing carbon dioxide to diffuse out of the tissue, cross the interstitial fluid, and enter the blood

We cannot return to the days of old when smoking was everywhere in offices, grocery stores, movie theaters, elevators, and airplanes

Withdrawal symptoms can be severe and may include cravings, anxiety, depression, and physical discomfort

The rigor and consistent application of these causal standards has rendered Surgeon General's Reports the preeminent source regarding whether cigarette smoking and exposure to secondhand smoke are causally related to specific negative health consequences